A ROS/GAS5/SIRT1 reinforcing feedback promotes oxidative stress-induced adipogenesis in bone marrow-derived mesenchymal stem cells during osteoporosis
Tao Lin, Zheng Zhang, Jinhui Wu, Heng Jiang, Ce Wang, Jun Ma, Yan Yin, Suchun Wang, Rui Gao, Xuhui Zhou
Topics & Concepts
AdipogenesisOil Red OFlow cytometryReactive oxygen speciesGAS5Oxidative stressMesenchymal stem cellOsteoblastChemistryCell biologyOsteoporosisDownregulation and upregulationEndocrinologyInternal medicineBiologyMedicineMolecular biologyIn vitroBiochemistryLong non-coding RNAGeneSirtuins and Resveratrol in MedicineExtracellular vesicles in diseasePhagocytosis and Immune Regulation