Single-Atom Indium Boosts Electrochemical Dopamine Sensing
Ruimin Li, Weiwei Guo, Zhijun Zhu, Yanling Zhai, Guanwen Wang, Zheng Liu, Lei Jiao, Chengzhou Zhu, Xiaoquan Lu
Abstract
A rational design of high-efficiency electrocatalysts and thus achieving sensitive electrochemical sensing remains a great challenge. In this work, single-atom indium anchored on nitrogen-doped carbon (In 1 –N–C) with an In–N 4 configuration is prepared successfully through a high-temperature annealing strategy; the product can serve as an advanced electrocatalyst for sensitive electrochemical sensing of dopamine (DA). Compared with In nanoparticle catalysts, In 1 –N–C exhibits high catalytic performance for DA oxidation. The theoretical calculation reveals that In 1 –N–C has high adsorption energy for hydroxy groups and a low energy barrier in the process of DA oxidation compared to In nanoparticles, indicating that In 1 –N–C with atomically dispersed In–N 4 sites possesses enhanced intrinsic activity. An electrochemical sensor for DA detection is established as a concept application with high sensitivity and selectivity. Furthermore, we also verify the feasibility of In 1 –N–C catalysts for the simultaneous detection of uric acid, ascorbic acid, and DA. This work extends the application prospect of p-block metal single-atom catalysts in electrochemical sensing.