CerS6 triggered by high glucose activating the TLR4/IKKβ pathway regulates ferroptosis of LO2 cells through mitochondrial oxidative stress
Dan Li, Ling Tian, Ping Nan, Jun Zhang, Zheng Yin, Xinxin Jia, Yihui Gong, Zhongming Wu
Topics & Concepts
Oxidative stressReactive oxygen speciesMitochondrionLipid peroxidationMitochondrial ROSAntioxidantOxidative phosphorylationProgrammed cell deathCell biologyBiologyChemistryApoptosisBiochemistryFerroptosis and cancer prognosisCancer-related molecular mechanisms researchCancer, Lipids, and Metabolism