Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking
Zhenqiu Huang, Shixiang Sun, Moonsook Lee, Alexander Y. Maslov, Miao Shi, S. Waldman, A. Marsh, T. Siddiqui, Xiao Dong, Yakov Peter, Ali Sadoughi, Chirag Shah, Kenny Ye, Simon D. Spivack, Jan Vijg
Topics & Concepts
Somatic cellLung cancerBiologyMutationGermline mutationMutation rateMutation frequencyGeneticsGeneMutation AccumulationLungCancer researchInternal medicineMedicineCancer Genomics and DiagnosticsSingle-cell and spatial transcriptomicsEpigenetics and DNA Methylation