Visible-light-promoted iron-catalyzed C–H functionalization of 1,4-naphthoquinones <i>via</i> oxidative coupling with sulfoximines
Alpa Sharma, Harpreet Kour, Jaspreet Kour, kamal kamal, Sanghapal D. Sawant
Abstract
C-H functionalization has been achieved using an iron catalytic system, which exhibits good reactivity and high regioselectivity in the presence of visible light. This is the first report offering an efficient protocol for obtaining (naphtho)quinone-sulfoximine hybrid analogs in moderate to good yields with wide scope for both the substrates. This protocol has also been applied on natural products for their modification, including vitamin K3, Juglone and some other modified natural scaffolds as well.
Topics & Concepts
Surface modificationRegioselectivityChemistryCatalysisOxidative coupling of methaneCombinatorial chemistryJugloneOxidative phosphorylationReactivity (psychology)PhotochemistryOrganic chemistryPathologyBiochemistryMedicinePhysical chemistryAlternative medicineCatalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsSulfur-Based Synthesis Techniques