Nerve Autografts Versus Allografts for Mixed Motor/Sensory Nerve Reconstruction
Sara Saffari, Alexander Y. Shin, Nicholas Pulos
Abstract
Reconstruction of peripheral mixed motor/sensory nerves using autografts has remained the gold standard. Inconsistent and nonphysiologic results across nerve allograft studies, including successful and failed motor reinnervation, have limited the current clinical application of nerve allografts to noncritical small-diameter sensory nerve defects less than 3 cm. This scoping review aimed to compare outcomes in both basic science and clinical applications of autograft and allograft nerve reconstruction for mixed motor/sensory nerves.
Topics & Concepts
ReinnervationMedicineSensory systemSensory nerveMotor nerveEpineurial repairPeripheral nervePeripheralTransplantationAnatomySurgeryNeurosciencePsychologyInternal medicineNerve Injury and RehabilitationNerve injury and regenerationOrgan and Tissue Transplantation Research