Intercalating methylene blue in molecular beacon for sensitive detection of salivary TNF-α towards early diagnosis of oral cancer
Siyi Zou, Hui Wei, Xiaolin Cui, Wing Cheung Mak, Xuejin Li, Guozhen Liu
Abstract
An electrochemical molecular beacon-based biosensor is developed for the sensitive detection of TNF-α, which presents a non-invasive strategy for salivary cytokines detection towards the early diagnosis of oral cancer in a point-of-care fashion.
Topics & Concepts
Methylene blueMolecular beaconMedicineSalivaCancerCancer detectionIntercalation (chemistry)Cancer researchChemistryInternal medicineBiochemistryGeneInorganic chemistryPhotocatalysisCatalysisOligonucleotideAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryAdvanced Biosensing Techniques and Applications