The tyrosine phosphatase SHP2 promotes proliferation and oxaliplatin resistance of colon cancer cells through AKT and ERK
Mengchao Yu, Chengzhen Xu, Hongwei Zhang, Jie Lun, Lei Wang, Gang Zhang, Jing Fang
Topics & Concepts
OxaliplatinProtein kinase BMAPK/ERK pathwayCancer researchGene knockdownCell growthApoptosisProtein tyrosine phosphataseChemistryCancer cellPhosphorylationCancerColorectal cancerBiologyMedicineInternal medicineBiochemistryProtein Tyrosine PhosphatasesGalectins and Cancer BiologyATP Synthase and ATPases Research