Colorimetric immunosensor constructed using 2D metal–organic framework nanosheets as enzyme mimics for the detection of protein biomarkers
Yujing Zeng, Minghui Wang, Zhaowei Sun, Lingjun Sha, Jie Yang, Genxi Li
Abstract
. Moreover, the sensor can successfully distinguish the human serum of colorectal cancer patients from healthy people, which suggests that this sensor has great potential in clinical applications. More importantly, the mass production, low cost, stability and ease of transport of the MOFs nanomaterials, as well as the ability for visual detection will make this sensor suitable for point-of-care (POC) testing in remote or resource-poor areas.
Topics & Concepts
AptamerDetection limitNanomaterialsCarcinoembryonic antigenNanotechnologyMaterials scienceLinear rangeProtein detectionChromatographyCombinatorial chemistryChemistryMolecular biologyCancerBiologyGeneticsAdvanced biosensing and bioanalysis techniquesAdvanced Nanomaterials in CatalysisBiosensors and Analytical Detection