Over time relationship between platelet reactivity, myocardial injury and mortality in patients with SARS-CoV-2-associated respiratory failure
Gianluca Campo, Marco Contoli, Alberto Fogagnolo, Francesco Vieceli Dalla Sega, Ottavio Zucchetti, Luca Ronzoni, Marco Verri, Francesca Fortini, Rita Pavasini, Luca Morandi, Simone Biscaglia, Luca Di Ienno, Emanuele D’Aniello, Marco Manfrini, Roberto Zoppellari, Paola Rizzo, Roberto Ferrari, Carlo Alberto Volta, Alberto Papi, Savino Spadaro
Abstract
< .05 for all). Myocardial injury was an independent predictor of mortality. In COVID-19 patients admitted to hospital for respiratory failure, heightened platelet activation is associated with severity of illness, myocardial injury, and mortality.ClinicalTrials.gov number: NCT04343053.
Topics & Concepts
MedicineInternal medicineRespiratory failureSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)CardiologyRespiratory systemPlateletCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakVirologyDiseaseInfectious disease (medical specialty)OutbreakCOVID-19 Clinical Research StudiesVenous Thromboembolism Diagnosis and ManagementAcute Myocardial Infarction Research