LncRNA THRIL, transcriptionally activated by AP-1 and stabilized by METTL14-mediated m6A modification, accelerates LPS-evoked acute injury in alveolar epithelial cells
Qian Shi, Zhiliang Li, Yixin Dong, Guigui Yang, Miao Li, Miao Li
Topics & Concepts
ARDSGene knockdownProinflammatory cytokineAutophagyA549 cellDownregulation and upregulationInflammationTranscription factorTumor necrosis factor alphaImmunologyCell biologyChemistryMolecular biologyCancer researchMedicineBiologyLungInternal medicineApoptosisGeneBiochemistryRNA modifications and cancerCancer-related molecular mechanisms researchHVDC Systems and Fault Protection