Structural and dynamic effects of paraoxon binding to human acetylcholinesterase by X-ray crystallography and inelastic neutron scattering
Oksana Gerlits, Mikolai Fajer, Xiaolin Cheng, Donald Blumenthal, Zoran Radić, Andrey Kovalevsky
Topics & Concepts
ParaoxonChemistryMolecular dynamicsAcetylcholinesteraseRational designStereochemistryBiophysicsCrystallographyComputational chemistryEnzymeBiochemistryMaterials scienceNanotechnologyBiologyCholinesterase and Neurodegenerative DiseasesPesticide Exposure and ToxicityChemical Reaction Mechanisms