Litcius/Paper detail

Incubating Green Synthesized Iron Oxide Nanorods for Proteomics-Derived Motif Exploration: A Fusion to Deep Learning Oncogenesis

Yasmeen Manzoor, Murtaza Hasan, Ayesha Zafar, Momina Dilshad, Muhammad Mahmood Ahmed, Tuba Tariq, Shahzad Hassan, Shahbaz Gul Hassan, Aqeela Shaheen, Giovanni Caprioli, Xugang Shu

2022ACS Omega17 citationsDOIOpen Access PDF

Abstract

and were well characterized using UV-visible spectroscopy, X-ray diffraction analysis, Fourier transform infrared spectroscopy, and nano-LC mass spectrophotometry. Iron oxides were rod-shaped with an average size of 17.32 nm and have crystalline properties. The as-synthesized nanotool mediated firm nano biointeraction with the proteins in treatment with nine different cancers. The resultant of the proteome series was filtered oddly that highlighted the variant proteins within the differentially expressed proteins on behalf of nano-bioinformatics. Further magnification focused on S13_N, RS15, RAB, and 14_3_3 domains and few abundant motifs that aid scanning biomarkers. The entire set of variant proteins contracting to common proteins elucidates the underlining mechanical proteins that are marginally assessed using the robotic nanotechnology. Additionally, the iron rods indirectly possess a prognostic effect in manipulating expression of proteins through a smarter route. Thereby, such biologically designed nanotools provide a dual approach for medical studies.

Topics & Concepts

ProteomeNanorodProteomicsNanotechnologyChemistryBiomoleculeNanomaterialsMaterials scienceNanoparticleComputational biologyBiologyBiochemistryGeneAdvanced Proteomics Techniques and ApplicationsAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical Detection