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Electrochemically Enabled Sulfonylation of Alkynes with Sodium Sulfinates

Xiangtai Meng, Hehua Xu, Xiaoji Cao, Xu‐Min Cai, Jinyue Luo, Fei Wang, Shenlin Huang

2020Organic Letters49 citationsDOI

Abstract

An electrochemical sulfonylation of alkynes with sodium sulfinates was achieved for the first time at room temperature. Employing this electrolysis strategy, the reaction occurs efficiently under transition-metal-free, external oxidant-free, and base-free conditions and furnishes diverse alkynyl sulfones in satisfactory yield with broad functional group tolerance.

Topics & Concepts

ChemistryElectrolysisYield (engineering)SodiumElectrochemistryBase (topology)Combinatorial chemistryFunctional groupOrganic chemistryElectrodeMetallurgyPhysical chemistryPolymerMathematical analysisElectrolyteMaterials scienceMathematicsSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsChemical Synthesis and Reactions