FTY720 (Fingolimod), a modulator of sphingosine-1-phosphate receptors, increases baseline hypothalamic-pituitary adrenal axis activity and alters behaviors relevant to affect and anxiety
Brian F. Corbett, Sandra Luz, Nathaniel Sotuyo, Jiah Pearson-Leary, Ganesh S. Moorthy, Athena F. Zuppa, Seema Bhatnagar
Topics & Concepts
EndocrinologyInternal medicineCorticosteroneFingolimodAdrenocorticotropic hormonePrefrontal cortexReceptorAnxiolyticNeuroscienceMedicinePsychologyHormoneMultiple sclerosisImmunologyCognitionSphingolipid Metabolism and SignalingNeuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders