TMVR for the Treatment of Mitral Regurgitation: A State-of-the-Art Review
Francesco Tartaglia, Giulia Antonelli, Mauro Gitto, Kamil Stankowski, Dario Donia, Giulio Stefanini, Azeem Latib, Antonio Colombo, Antonio Mangieri, Mauro Chiarito
Abstract
Mitral regurgitation is the most common valve disease worldwide. Despite its wide success in inoperable or high-risk surgical patients, transcatheter edge-to-edge repair remains limited by some anatomic features and the non-negligible rate of significant residual regurgitation. Transcatheter mitral valve replacement has emerged as a viable alternative that promises to overcome these issues, but its development has been progressing slowly. This review aims to provide a comprehensive overview of the current state of transcatheter mitral valve replacement, including patient selection, procedural techniques, and currently available outcomes.