Necroptosis in bacterial infections
Xing Yu, Jin Yuan, Lin-xi Shi, Shuying Dai, Lei Yue, Min Yan
Abstract
Necroptosis, a recently discovered form of cell-programmed death that is distinct from apoptosis, has been confirmed to play a significant role in the pathogenesis of bacterial infections in various animal models. Necroptosis is advantageous to the host, but in some cases, it can be detrimental. To understand the impact of necroptosis on the pathogenesis of bacterial infections, we described the roles and molecular mechanisms of necroptosis caused by different bacterial infections in this review.
Topics & Concepts
NecroptosisPathogenesisProgrammed cell deathBiologyApoptosisImmunologyGeneticsCell death mechanisms and regulationStreptococcal Infections and TreatmentsImmune Response and Inflammation