Litcius/Paper detail

Deubiquitinating enzyme OTUB1 promotes cancer cell immunosuppression via preventing ER-associated degradation of immune checkpoint protein PD-L1

Dan Zhu, Ruidan Xu, Xinping Huang, Zefang Tang, Yonglu Tian, Jinfang Zhang, Xiaofeng Zheng

2020Cell Death and Differentiation178 citationsDOIOpen Access PDF

Topics & Concepts

Deubiquitinating enzymePD-L1Cancer researchImmune systemImmune checkpointImmunotherapyCancer immunotherapyChemistryCancer cellCancerUbiquitinBiologyImmunologyBiochemistryGeneticsGeneUbiquitin and proteasome pathwaysPeptidase Inhibition and AnalysisAutophagy in Disease and Therapy
Deubiquitinating enzyme OTUB1 promotes cancer cell immunosuppression via preventing ER-associated degradation of immune checkpoint protein PD-L1 | Litcius