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Single-cell ATAC-seq maps the comprehensive and dynamic chromatin accessibility landscape of CAR-T cell dysfunction

Penglei Jiang, Zhaoru Zhang, Yongxian Hu, Zuyu Liang, Yingli Han, Xia Li, Xin Zeng, Hao Zhang, Meng Zhu, Jian Dong, He Huang, Pengxu Qian

2022Leukemia47 citationsDOI

Topics & Concepts

Chimeric antigen receptorChromatinIRF4HaematopoiesisBiologyEpigeneticsCancer researchT cellCellImmunologyCell biologyStem cellTranscription factorGeneticsGeneImmune systemCAR-T cell therapy researchAdvancements in Semiconductor Devices and Circuit DesignViral Infectious Diseases and Gene Expression in Insects
Single-cell ATAC-seq maps the comprehensive and dynamic chromatin accessibility landscape of CAR-T cell dysfunction | Litcius