Long-read sequencing on the SMRT platform enables efficient haplotype linkage analysis in preimplantation genetic testing for β-thalassemia
Haitao Wu, Dongjia Chen, Qiang Zhao, Xiaoting Shen, Yong-bin Liao, Ping Li, Philip C.N. Chiu, Canquan Zhou
Topics & Concepts
Human geneticsHaplotypeGeneticsThalassemiaBiologyComputational biologyGenetic testingLinkage (software)GeneGenotypeHemoglobinopathies and Related DisordersPrenatal Screening and DiagnosticsGenomics and Rare Diseases