Intranasal Administration of Resolvin E1 Produces Antidepressant-Like Effects via BDNF/VEGF-mTORC1 Signaling in the Medial Prefrontal Cortex
Satoshi Deyama, Shun Aoki, Rinako Sugie, Hayato Fukuda, Satoshi Shuto, Masabumi Minami, Katsuyuki Kaneda
Topics & Concepts
AntidepressantPrefrontal cortexPharmacologymTORC1Neurotrophic factorsDentate gyrusEndocrinologyChemistryInternal medicineMedicineNeuroscienceHippocampusPsychologyReceptorPI3K/AKT/mTOR pathwaySignal transductionCognitionBiochemistryNeuroscience and Neuropharmacology ResearchTreatment of Major DepressionStress Responses and Cortisol