Sustained release polymer and surfactant based solid dispersion of andrographolide exhibited improved solubility, dissolution, pharmacokinetics, and pharmacological activity
Syed Assim Haq, Gourav Paudwal, Nagma Banjare, Nusrit Iqbal Andrabi, Priya Wazir, Utpal Nandi, Zabeer Ahmed, Prem N. Gupta
Topics & Concepts
SolubilityAndrographolideDifferential scanning calorimetryBioavailabilityDissolutionChemistryFourier transform infrared spectroscopyPharmacokineticsChromatographyPoloxamerNuclear chemistryPharmacologyMaterials scienceChemical engineeringPolymerOrganic chemistryMedicineThermodynamicsEngineeringPhysicsCopolymerAndrographolide Research and ApplicationsDrug Solubulity and Delivery SystemsDrug Transport and Resistance Mechanisms