Mass spectrometry-based multi-attribute method for mutation analysis in the early development of therapeutic proteins
Tao Liu, Yantao Li, Jin Xu, Qingcheng Guo, Lei Zhu, Tuo Fu, Jun Li, Dapeng Zhang, Weizhu Qian, Xinli Zhou, Huaizu Guo, Sheng Hou
Topics & Concepts
BioprocessChemistryDrug developmentComputational biologyMutantProcess developmentMass spectrometryDNA sequencingMutationChromatographyDNABiochemistryDrugBiologyPharmacologyGeneProcess managementPaleontologyBusinessMonoclonal and Polyclonal Antibodies ResearchViral Infectious Diseases and Gene Expression in InsectsProtein purification and stability