Litcius/Paper detail

Overcoming the Hurdles and Challenges Associated with Developing Continuous Industrial Processes

Marcus Baumann, Thomas S. Moody, Megan Smyth, Scott Wharry

2020European Journal of Organic Chemistry49 citationsDOI

Abstract

Continuous flow chemistry is often viewed as a very simple concept on paper, however scientists with significant flow chemistry experience will highlight a number of challenges that need to be overcome. Critical for the successful development of any flow process is a high level of understanding of potential pitfalls that may be encountered. A collaborative and multi‐disciplinary team of chemists and chemical engineers is essential in the development of a process from lab scale through to production. This Minireview will identify and highlight relevant risks and their subsequent mitigation strategies to ensure successful flow processing.

Topics & Concepts

Continuous flowProcess developmentProcess (computing)Flow chemistryScale (ratio)ChemistryBiochemical engineeringEngineering ethicsNanotechnologyManagement scienceRisk analysis (engineering)Computer scienceProcess managementEngineeringBusinessPhysicsQuantum mechanicsOperating systemMaterials scienceInnovative Microfluidic and Catalytic Techniques InnovationMicrofluidic and Capillary Electrophoresis Applications