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Controlling Synthetic Cell-Cell Communication

Jefferson M. Smith, Razia Chowdhry, Michael J. Booth

2022Frontiers in Molecular Biosciences48 citationsDOIOpen Access PDF

Abstract

Synthetic cells, which mimic cellular function within a minimal compartment, are finding wide application, for instance in studying cellular communication and as delivery devices to living cells. However, to fully realise the potential of synthetic cells, control of their function is vital. An array of tools has already been developed to control the communication of synthetic cells to neighbouring synthetic cells or living cells. These tools use either chemical inputs, such as small molecules, or physical inputs, such as light. Here, we examine these current methods of controlling synthetic cell communication and consider alternative mechanisms for future use.

Topics & Concepts

Synthetic biologyArtificial cellCell functionCellular communicationFunction (biology)CellComputer scienceBiologyCell biologyComputational biologyTelecommunicationsBiochemistryMembraneWirelessMolecular Communication and NanonetworksPhotoreceptor and optogenetics researchAdvanced biosensing and bioanalysis techniques
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