Organocatalytic Enantioselective α-Nitrogenation of α,α-Disubstituted Aldehydes in the Absence of a Solvent
Alejandro Torregrosa‐Chinillach, Asier Carral‐Menoyo, Enrique Gómez‐Bengoa, Rafael Chinchílla
Abstract
. The sustainability of the procedure was established through the calculation of green metrics, such as EcoScale and E-factor. In addition, theoretical calculations have been used to justify the obtained enantioselectivity sense.
Topics & Concepts
Enantioselective synthesisChemistrySolventCarbamateOrganic chemistryDiamineOrganocatalysisCatalysisCarbon dioxide utilization in catalysisAsymmetric Hydrogenation and CatalysisChemical Synthesis and Reactions