2-Methoxy-6-acetyl-7-methyljuglone (MAM) induced programmed necrosis in glioblastoma by targeting NAD(P)H: Quinone oxidoreductase 1 (NQO1)
Jie Yu, Bingling Zhong, Long Jin, Ying Hou, Nana Ai, Wei Ge, Luoxiang Li, Shuqin Liu, Jin‐Jian Lu, Xiuping Chen
Topics & Concepts
GlioblastomaNAD+ kinaseQuinoneChemistryOxidoreductaseIDH1StereochemistryCancer researchBiochemistryBiologyEnzymeGeneMutationBioactive Compounds and Antitumor AgentsCancer therapeutics and mechanismsGenomics, phytochemicals, and oxidative stress