Sonodynamic amplification of cGAS-STING activation by cobalt-based nanoagonist against bone and metastatic tumor
Jie Lei, Weifeng Zhang, Liang Ma, Yaqi He, Huaizhen Liang, Xiaoguang Zhang, Gaocai Li, Xiaobo Feng, Lei Tan, Yang Cao
Topics & Concepts
StingStimulator of interferon genesCancer researchSonodynamic therapyProinflammatory cytokineTumor microenvironmentAbscopal effectImmunotherapyMaterials scienceInnate immune systemApoptosisMedicineChemistryImmunologyImmune systemInflammationBiochemistryTumor cellsAerospace engineeringEngineeringinterferon and immune responsesRNA modifications and cancerNanoplatforms for cancer theranostics