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6-methoxydihydroavicine, the alkaloid extracted from Macleaya cordata (Willd.) R. Br. (Papaveraceae), triggers RIPK1/Caspase-dependent cell death in pancreatic cancer cells through the disruption of oxaloacetic acid metabolism and accumulation of reactive oxygen species

Nengfang Ma, Fugen Shangguan, Hongfei Zhou, Huimin Huang, Jun Lei, Jing An, Guihua Jin, Weiwei Zhuang, Shipeng Zhou, Shijia Wu, Hongping Xia, Hailong Yang, Linhua Lan

2022Phytomedicine22 citationsDOI

Topics & Concepts

ApoptosisProgrammed cell deathCancer cellBiologyBiochemistryChemistryCell biologyPharmacologyCancerGeneticsBerberine and alkaloids researchAlkaloids: synthesis and pharmacologyTraditional and Medicinal Uses of Annonaceae
6-methoxydihydroavicine, the alkaloid extracted from Macleaya cordata (Willd.) R. Br. (Papaveraceae), triggers RIPK1/Caspase-dependent cell death in pancreatic cancer cells through the disruption of oxaloacetic acid metabolism and accumulation of reactive oxygen species | Litcius