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Pharmacological inhibition of IRAK1 and IRAK4 prevents endothelial inflammation and atherosclerosis in ApoE-/- mice

Xiumei Wu, Mengyun Xu, Zhenghong Liu, Zhidan Zhang, Yujie Liu, Sihui Luo, Xueying Zheng, Peter J. Little, Suowen Xu, Jianping Weng

2021Pharmacological Research21 citationsDOI

Topics & Concepts

InflammationMedicineEndotheliumEndothelial dysfunctionPharmacologyEndothelial activationImmunologyCancer researchInternal medicineImmune Response and InflammationPeroxisome Proliferator-Activated ReceptorsAdipokines, Inflammation, and Metabolic Diseases
Pharmacological inhibition of IRAK1 and IRAK4 prevents endothelial inflammation and atherosclerosis in ApoE-/- mice | Litcius