Litcius/Paper detail

The On- and Off-Ramps of Oncology Accelerated Approval

Lola A. Fashoyin‐Aje, Gautam U. Mehta, Julia A. Beaver, Richard Pazdur

2022New England Journal of Medicine81 citationsDOI

Abstract

To address ongoing concerns about the implementation of the FDA’s Accelerated Approval pathway in oncology, a comprehensive strategy is needed — one that equally emphasizes “on-ramp” and “off-ramp” considerations.

Topics & Concepts

MedicineDrug approvalMEDLINEOncologyInternal medicineIntensive care medicinePharmacologyPolitical scienceLawDrugStatistical Methods in Clinical TrialsHealth Systems, Economic Evaluations, Quality of LifeBiomedical Ethics and Regulation