Multi-layered alginate hydrogel structures and bacteria encapsulation
Yoon Jeong, Joseph Irudayaraj
Abstract
We show the design and fabrication of finely tuned alginate core-shell capsules with precisely controllable core and hierarchical shell thickness at micron scale for scaleup for mass production. The method developed was used to encapsulate bacteria while maintaining morphology and mechanical stability of the bead without rupturing and cell leakage.
Topics & Concepts
Cell encapsulationFabricationMaterials scienceEncapsulation (networking)NanotechnologyChemical engineeringSelf-healing hydrogelsPolymer chemistryComputer scienceAlternative medicineMedicinePathologyEngineeringComputer network3D Printing in Biomedical ResearchHydrogels: synthesis, properties, applicationsPancreatic function and diabetes