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Formaldehyde induces ferroptosis in hippocampal neuronal cells by upregulation of the Warburg effect

Xiaona Li, San‐Qiao Yang, Min Li, Xuesong Li, Qing Tian, Fan Xiao, Yi-Yun Tang, Xuan Kang, Chunyan Wang, Wei Zou, Ping Zhang, Xiao‐Qing Tang

2020Toxicology50 citationsDOI

Topics & Concepts

Warburg effectNeurotoxicityDownregulation and upregulationChemistryLactate dehydrogenase AProgrammed cell deathLactate dehydrogenaseReactive oxygen speciesOxidative stressPyruvate dehydrogenase complexCell biologyMitochondrionPyruvate kinaseViability assayBiologyBiochemistryMolecular biologyGlycolysisCellMetabolismApoptosisToxicityEnzymeOrganic chemistryGeneFerroptosis and cancer prognosisMicroRNA in disease regulationGenomics, phytochemicals, and oxidative stress
Formaldehyde induces ferroptosis in hippocampal neuronal cells by upregulation of the Warburg effect | Litcius