Litcius/Paper detail

Protein degraders enter the clinic — a new approach to cancer therapy

Deborah Chirnomas, Keith R. Hornberger, Craig M. Crews

2023Nature Reviews Clinical Oncology599 citationsDOIOpen Access PDF

Topics & Concepts

MedicineProtein degradationComputational biologyProteasomeClinical trialBioinformaticsBiologyBiochemistryInternal medicineProtein Degradation and InhibitorsPeptidase Inhibition and AnalysisUbiquitin and proteasome pathways