Litcius/Paper detail

Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation and the MAPK signaling pathway in high-fat diet/streptozotocin-induced diabetic mice

Yanyan Zhu, Chenhui Zhu, Haixia Yang, Jianjun Deng, Daidi Fan

2020Pharmacological Research150 citationsDOI

Topics & Concepts

TXNIPDiabetic nephropathyStreptozotocinOxidative stressEndocrinologyChemistryKidneyInternal medicineInflammasomep38 mitogen-activated protein kinasesProinflammatory cytokinePharmacologyDiabetes mellitusMAPK/ERK pathwayMedicineKinaseInflammationBiochemistryThioredoxinGinseng Biological Effects and ApplicationsLipid metabolism and disordersInflammasome and immune disorders