Salidroside can target both P4HB-mediated inflammation and melanogenesis of the skin
Xiujuan Ding, Zhiyuan Zhang, Jing Jin, Jingxia Han, Yan Wang, Kai Yang, Yuyan Yang, Hongqi Wang, Xintong Dai, Cheng Yao, Tao Sun, Caibin Zhu, Huijuan Liu
Abstract
SAL can inhibit the inflammation and melanogenesis of the skin by targeting P4HB and regulating the formation of the IRF1/USF1 transcription complex. In addition, SAL-plus may be a new melanin production and inflammatory inhibitor.
Topics & Concepts
SalidrosideInflammationChemistryPsoriasisPharmacologyMedicineDermatologyInternal medicineMedicinal Plants and Bioactive CompoundsFlavonoids in Medical ResearchSaffron Plant Research Studies