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Photocatalyst- and additive-free decarboxylative alkylation of<i>N</i>-aryl tetrahydroisoquinolines induced by visible light

Pengju Ma, Yufei Liu, Lingling Chen, Xu Zhao, Bo Yang, Junmin Zhang

2021Organic Chemistry Frontiers34 citationsDOI

Abstract

A photocatalyst- and additive-free visible light induced decarboxylative alkylation of<italic>N</italic>-aryl tetrahydroisoquinolines has been developed using tetrachloro-<italic>N</italic>-hydroxyphthalimide esters as alkylation agents.

Topics & Concepts

AlkylationChemistryPhotocatalysisArylVisible spectrumMedicinal chemistryOrganic chemistryCatalysisPhotochemistryAlkylOptoelectronicsPhysicsRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques
Photocatalyst- and additive-free decarboxylative alkylation of<i>N</i>-aryl tetrahydroisoquinolines induced by visible light | Litcius