Biomarker-activated multifunctional lysosome-targeting chimeras mediated selective degradation of extracellular amyloid fibrils
Zhenqi Liu, Qingqing Deng, Geng Qin, Jie Yang, Haochen Zhang, Jinsong Ren, Xiaogang Qu
Topics & Concepts
LysosomeCell biologyExtracellularAmyloid βAmyloid (mycology)BiomarkerChemistryBiologyBiochemistryMedicinePathologyDiseaseInorganic chemistryEnzymeRNA Interference and Gene DeliveryProtein Degradation and InhibitorsDendrimers and Hyperbranched Polymers