Litcius/Paper detail

Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1

Jianmin Zhang, J Roberts, Fei Chang, Joon Schwakopf, Monica L. Vetter

2023Cell Reports13 citationsDOIOpen Access PDF

Abstract

(Cell Reports 42, 112237; March 28, 2023) In the originally published version of this article, an error was introduced in Figure 7C as files were prepared for production, resulting in an incorrect violin plot shown for Sfrp2. The corrected figure is now provided, and the original article has been updated. The authors regret this error. Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1Zhang et al.Cell ReportsMarch 14, 2023In BriefTemporal patterning of neural progenitors is essential to generate neuronal diversity. Zhang et al. find that Jarid2 facilitates retinal progenitor temporal identity transition via H3K27me3 deposition and repression of early genes, most notably Foxp1. They find that Foxp1 is an effector of Jarid2 in regulating timing of retinal neurogenesis. Full-Text PDF Open Access

Topics & Concepts

Psychological repressionProgenitor cellRetinalProgenitorBiologyRegretComputer scienceNeuroscienceCell biologyStem cellGeneGeneticsBotanyGene expressionMachine learningRetinal Development and DisordersCell Image Analysis TechniquesAdvanced Fluorescence Microscopy Techniques