Environmental six-ring polycyclic aromatic hydrocarbons are potent inducers of the AhR-dependent signaling in human cells
Jan Vondráček, Kateřina Pěnčíková, Miroslav Cigánek, Jakub Pivnička, Martina Karasová, Martina Hýžďalová, Simona Strapáčová, Lenka Pálková, Jiřı́ Neča, Jason Matthews, Michal Lom, Jan Topinka, Alena Milcová, Miroslav Machala
Topics & Concepts
Aryl hydrocarbon receptorFluorantheneGenotoxicityChemistryEnvironmental chemistryPolycyclic aromatic hydrocarbonInducerAryl hydrocarbon receptor nuclear translocatorMode of actionToxicityBiochemistryGeneOrganic chemistryTranscription factorPhenanthreneToxic Organic Pollutants ImpactEffects and risks of endocrine disrupting chemicalsCarcinogens and Genotoxicity Assessment