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Pyridine <i>N</i> -oxides as HAT reagents for photochemical C–H functionalization of electron-deficient heteroarenes

Łukasz W. Ciszewski, Dorota Gryko

2022Chemical Communications26 citationsDOIOpen Access PDF

Abstract

-oxide precludes the need for a photocatalyst. The developed method allows for a broad range of radical precursors to be used, namely alkanes, alkenes, amides, and ethers, for efficient alkylation of azines.

Topics & Concepts

ReagentChemistryAlkylationPhotocatalysisPhotochemistryPyridineReactivity (psychology)Hydrogen atomSurface modificationSubstrate (aquarium)Electron transferSalt (chemistry)OxideCombinatorial chemistryOrganic chemistryCatalysisAlkylPhysical chemistryOceanographyPathologyGeologyMedicineAlternative medicineRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSynthesis and Catalytic Reactions
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