TGF-β loaded exosome enhances ischemic wound healing <i>in vitro</i> and <i>in vivo</i>
Ao Shi, Jialun Li, Xinyuan Qiu, Michael S. Sabbah, Soulmaz Boroumand, Tony Chieh‐Ting Huang, Chunfeng Zhao, André Terzic, Atta Behfar, Steven L. Moran
Abstract
This room-temperature stable, lyophilized exosome product is thus capable of delivering a bioactive transforming growth factor beta to drive regenerative events.
Topics & Concepts
ExosomeIn vivoWound healingIn vitroMedicineMicrovesiclesPharmacologyCancer researchChemistrySurgeryBiologyBiochemistryBiotechnologymicroRNAGeneWound Healing and TreatmentsExtracellular vesicles in diseasePeriodontal Regeneration and Treatments