Sinapic Acid Attenuated Cisplatin-Induced Cardiotoxicity by Inhibiting Oxidative Stress and İnflammation with GPX4-Mediated NF-kB Modulation
Caner Yıldırım, Sibel Cangi, Mustafa Örkmez, Şenay Görücü Yılmaz, Mehmet Akif Bozdayı, Hatice Yamaner, Sena Çevik
Topics & Concepts
Oxidative stressCardiotoxicityCisplatinChemistryPharmacologyReactive oxygen speciesNF-κBAntioxidantMedicineCancer researchApoptosisBiochemistryInternal medicineToxicityChemotherapyChemotherapy-induced organ toxicity mitigationChemotherapy-induced cardiotoxicity and mitigationParaoxonase enzyme and polymorphisms