Detection of Mixed Populations of Clarithromycin-Susceptible and -Resistant Mycobacterium abscessus Strains
Shamira J. Shallom, Adrian M. Zelazny
Abstract
Clarithromycin resistance in Mycobacterium abscessus subsp. abscessus , massiliense , and bolletii occurs through induction of erm (41) or mutations in rrl (23S rRNA) genes. Phenotypic detection of clarithromycin resistance is hindered by the need for extended incubation as well as co-occurrence of mixed populations of M. abscessus
Topics & Concepts
Clarithromycin23S ribosomal RNAMycobacterium abscessusMicrobiologyBiologyEtestDrug resistanceMycobacteriumVirologyAntibioticsMolecular biologyGeneGeneticsBacteriaRNARibosomeMycobacterium research and diagnosisTuberculosis Research and EpidemiologyInfectious Diseases and Mycology