Mechanisms of selected functional foods against viral infections with a view on COVID-19: Mini review

Alexander G. Haslberger, U. Jacob, Berit Hippe, Heidrun Karlic

2020Functional Foods in Health and Disease61 citationsDOI Open Access PDF

Abstract

Following research obtained from the previous SARS and MERS outbreaks, we’ve gained knowledge about the mechanisms of bioactive plant ingredients against the attachment and replication of COVID-19 as well as overshooting immune responses. This could be used for designing COVID-19 trials utilizing bioactive compounds. The receptors for SARS, ACE-2, and CD26 show associations with mechanisms that regulate human senescence. Several functional foods interact with the epigenetic regulation of viral infection and mechanisms of senescence. This review concentrates on the link between bioactive plant ingredients and their activities against mechanisms of viral infections.Keywords: COVID-19, Epigenetic, Quercetin, Curcumin, Epigallocatechin gallate, Phloretin, Berberine

Topics & Concepts

Coronavirus disease 2019 (COVID-19)CurcuminBiologyEpigeneticsImmune systemSenescenceViral replicationPhloretinSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Caffeine2019-20 coronavirus outbreakPharmacologyComputational biologyVirusVirologyMedicineOutbreakBiochemistryImmunologyCell biologyDiseaseGenePathologyInfectious disease (medical specialty)EndocrinologyCurcumin's Biomedical ApplicationsNatural Antidiabetic Agents Studies