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A genome-wide analysis of the shared genetic risk architecture of complex neurological and psychiatric disorders

Olav B. Smeland, Gleda Kutrolli, Shahram Bahrami, Vera Fominykh, Nadine Parker, Julian Fuhrer, Guy Hindley, Linn Rødevand, Piotr Jahołkowski, Markos Tesfaye, Pravesh Parekh, Torbjørn Elvsåshagen, Andrew D. Grotzinger, Nils Eiel Steen, Dennis van der Meer, Kevin S. O’Connell, Srdjan Djurovic, Anders M. Dale, Alexey Shadrin, Oleksandr Frei, Ole A. Andreassen

2025Nature Neuroscience16 citationsDOI

Topics & Concepts

Genetic architecturePleiotropyPsychiatryGenetic associationDiseaseAssociation (psychology)Psychiatric DiseaseMedicinePsychologyNeuroscienceGenetic testingMental illnessGenetic predispositionEndophenotypeGenome-wide association studySet (abstract data type)Genetic variantsNeurological disorderGenetic syndromesNeuroimagingClinical psychologyGenetic modelPsychiatric geneticsGenetic Associations and EpidemiologyFunctional Brain Connectivity StudiesGenomics and Rare Diseases
A genome-wide analysis of the shared genetic risk architecture of complex neurological and psychiatric disorders | Litcius