CD32+CD4+ T Cells Are Highly Enriched for HIV DNA and Can Support Transcriptional Latency
Gilles Darcis, Neeltje A. Kootstra, Berend Hooibrink, Thijs van Montfort, Irma Maurer, Kevin Groen, Suzanne Jurriaans, Margreet Bakker, Carine Van Lint, Ben Berkhout, Alexander Pasternak
Abstract
T cells for future studies and indicate that CD32 remains a promising candidate marker of the HIV reservoir.
Topics & Concepts
Ex vivoBiologyDNARNAHuman immunodeficiency virus (HIV)CartVirus latencyVirologyMolecular biologyVirusIn vivoViral replicationGeneticsGeneEngineeringMechanical engineeringHIV Research and TreatmentImmune Cell Function and InteractionT-cell and B-cell Immunology