Conjugation of a cyclometalated Ir( <scp>iii</scp> ) complex to human serum albumin for oncosis-mediated photodynamic therapy
Antonio Linero-Artiaga, Lisa-Marie Servos, Zisis Papadopoulos, Venancio Rodrı́guez, José Ruiz, Johannes Karges
Abstract
We report on the first photo-responsive metallodrug–albumin conjugate capable of inducing oncosis in cancer cells.
Topics & Concepts
Photodynamic therapyChemistryHuman serum albuminAlbuminSerum albuminBiophysicsCancer researchMedicineBiochemistryBiologyOrganic chemistryNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesClick Chemistry and Applications