Total Synthesis of (−)-Cylindricine H
Miriam Piccichè, Alexandre Pinto, Rosa Griera, Joan Bosch, Mercedes Amat
Abstract
by intramolecular opening of an epoxide.
Topics & Concepts
StereocenterChemistryStereoselectivityIntramolecular forceEnantioselective synthesisPyrrolidineStereochemistryQuaternary carbonEpoxideTotal synthesisLactamRing (chemistry)Organic chemistryCatalysisAdvanced Synthetic Organic ChemistryChemical synthesis and alkaloidsAlkaloids: synthesis and pharmacology