IRAK1 Gene Polymorphism in Rheumatoid Arthritis
Najme Hosseini, Mohammad Taher Tahoori, Adel Mohammadzadeh, Hossein Zarei Jaliani, Morteza Bitaraf Sani, Hosein Soleimani Salehabadi
Abstract
: Our results showed that the rs1059703 T allele (risk allele) of IRAK1 gene increases the risk of RA and the severity of disease, affecting the onset age of RA in Iranian patients.
Topics & Concepts
GenotypeSingle-nucleotide polymorphismRheumatoid arthritisAlleleMedicineImmunologyArthritisGene polymorphismInternal medicineGeneGeneticsBiologyRheumatoid Arthritis Research and TherapiesToxin Mechanisms and ImmunotoxinsImmune Response and Inflammation